解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Pemphigus is a group of autoimmune diseases characterized by the formation of erosions and/or flaccid bullae of the skin and/or mucosae. The definition "drug-induced pemphigus" has been coined to indicate cases of pemphigus with clinical, histological and immunopathologic features similar to those of the idiopathic di...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12748
更新日期:2019-01-01 00:00:00
abstract::Pruritus is associated with various skin diseases, dry skin, and with it an impaired skin barrier function. The study objective was to investigate short-term and long-term effects of two emollients on symptoms and skin barrier functions in xerotic eczema. Randomized, double-blind, study enrolling females/males, with b...
journal_title:Dermatologic therapy
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/dth.12692
更新日期:2018-11-01 00:00:00
abstract::A 57-year-old Caucasian female presented to our clinic with her 23-year-old son, who was profoundly autistic. Our patient was convinced that her son had an infestation with fibers and believed that he had developed the condition as a young child. She described the symptoms of the infestation in her son's skin on his b...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12724
更新日期:2018-11-01 00:00:00
abstract::Ingrown nail is a common problem seen in the dermatology clinics. The aim of this study is to compare the wedge resection method and chemical matricectomy with NaOH in terms of operation time, postoperative pain severity, postoperative drainage, recurrence rates, recovery time, and the effects of these two methods on ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,随机对照试验
doi:10.1111/dth.12677
更新日期:2018-09-01 00:00:00
abstract::Most studies of oral oxybutynin (OOx) for the treatment of hyperhidrosis (HH) have assumed a stable treatment protocol, without taking into account adverse effects (AE) or seasonal variations in temperature. The objective is to evaluate adjusting the dose of OOx according to the time of year. Prospective study of pati...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12615
更新日期:2018-07-01 00:00:00
abstract::Despite the high prevalence of pulmonary tuberculosis worldwide, extrapulmonary tuberculosis especially cutaneous and osteoarticular tuberculosis occurs rarely, both of which are often difficult to be recognized since their symptoms mimic those of many other cutaneous and osteoarticular diseases. Here, we present a ra...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12600
更新日期:2018-07-01 00:00:00
abstract::Topical application of timolol cream is effective and convenient for treating superficial infantile hemangiomas. Intralesional injection of corticosteroids, such as diprospan, is useful for the treatment of superficia infantile hemangiomas without systemic side effects. We conducted a self-controlled study to investig...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12595
更新日期:2018-05-01 00:00:00
abstract::Psoriasis of the scalp, face, intertriginous areas, genitals, hands, feet, and nails is often underdiagnosed, and disease management can be challenging. Despite the small surface area commonly affected by psoriasis in these locations, patients have disproportionate levels of physical impairment and emotional distress....
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12589
更新日期:2018-05-01 00:00:00
abstract::Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group. Psoriasis in childhood is not uncommon and has genetic susceptibility but usually, an environmental trigger such as infection is thought to initiate the disease process. Pediatric psoriasis has profound effects on both physical a...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12571
更新日期:2018-01-01 00:00:00
abstract::Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male a...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12503
更新日期:2017-09-01 00:00:00
abstract::Oral lichen planus (OLP) is a chronic inflammatory disease, has prolonged courses, repeated attacks and resistance to treatment. The traditional narrow spectrum UVB treatment has an established efficacy on skin lichen planus, and high safety. However, most of ultraviolet phototherapy devices have a huge volume, thereb...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12510
更新日期:2017-09-01 00:00:00
abstract::Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans ("mucins"). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chro...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12504
更新日期:2017-07-01 00:00:00
abstract::Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12465
更新日期:2017-05-01 00:00:00
abstract::Axillary bromhidrosis has a strong negative effect on one's social life. A high success rate and few complications are criteria for a surgical treatment. The objective of this study was to evaluate a new surgical treatment modality for bromhidrosis: subcutaneous scissor with micropore. Twenty patients with bromhidrosi...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12484
更新日期:2017-05-01 00:00:00
abstract::Mycobacterium W (Mw) vaccine has been found to be effective in the treatment of leprosy and warts. Despite increasing use of Mw immunotherapy, data on its safety is limited. We report a series of eight patients who developed persisting injection site granulomatous reaction following Mw immunotherapy and were successfu...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12452
更新日期:2017-03-01 00:00:00
abstract::Prostaglandins and their analogues are beneficial as topical agents in vitiligo treatment, yet neither of the previous study addressed their comparative efficiency with conventional topical agents used in vitiligo treatment. In this pilot (24 patients) left-right comparative study we addressed efficiency of prostaglan...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12383
更新日期:2016-11-01 00:00:00
abstract::Acitretin has been used off-label for years to treat chronic hand eczema, but acitretin is less often prescribed as alitretinoïne was approved. This study evaluates both retinoids in a daily practice cohort of patients with severe chronic hand eczema in terms of drug survival and reasons for discontinuation. Patients ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12362
更新日期:2016-09-01 00:00:00
abstract::Although acne is not an infectious disease, oral antibiotics have remained a mainstay of treatment over the last 40 years. The anti-inflammatory properties of oral antibiotics, particularly the tetracyclines, are efficacious in treating inflammatory acne lesions. Common prescribing practices in Dermatology exert signi...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12370
更新日期:2016-09-01 00:00:00
abstract::Generalized eruptive keratoacanthoma, is considered a serious condition because the eruptions are diffuse, persistent, and recurrent. Constant pruritus, visceral neoplasms, and unsatisfactory response to treatment are ominous prognostic factors. Even if skin cancers are usually well controlled with surgical and/or rad...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12374
更新日期:2016-09-01 00:00:00
abstract::Surgery as treatment for local invasive cutaneous squamous cell carcinoma (cSCC) is not always feasible due to the age and/or the health status of patients. Thus, the investigation of new strategies to improve the quality of life of them is required. The aim of this work is to investigate two chemotherapy agents indiv...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12373
更新日期:2016-09-01 00:00:00
abstract::Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramati...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12337
更新日期:2016-05-01 00:00:00
abstract::Daylight-photodynamic therapy (D-PDT) and ingenol mebutate (IM) are novel therapies directed to actinic keratoses (AK). The purpose of our study was to compare effectiveness, tolerability, cosmetic outcome and patient preference of D-PDT versus IM in the treatment of grade I and II AK. Twenty-seven patients with AK on...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/dth.12334
更新日期:2016-05-01 00:00:00
abstract::Diphenylcyclopropenone (DPCP) immunotherapy has been shown to be efficacious for the treatment of warts, especially periungual warts for which destructive techniques are limited. However, factors affecting the duration of treatment of periungual warts have not been studied. A total of 61 patients with periungual warts...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12312
更新日期:2016-03-01 00:00:00
abstract::Large difficult to heal ulcers of various etiologies carry a high morbidity and mortality rate. Becaplermin is a recombinant platelet-derived growth factor approved for treatment of diabetic ulcers. In this two-case series, we report the use of becaplermin in the treatment of ulcers due to (i) calciphylaxis, an often ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12318
更新日期:2016-03-01 00:00:00
abstract::Chronic pruritus is a common dermatological condition affecting 10-13% of the general population. UVB phototherapy has been demonstrated to be effective in relieving the symptoms of pruritus. However, phototherapy is rarely administered because the treatment is time-consuming and expensive, when compared to other topi...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12309
更新日期:2016-03-01 00:00:00
abstract::Malignant melanoma is considered to be an immunogenic tumor, which is expected to change its behaviour in the field of immunosuppression. Although the incidence of melanoma in organ transplant recipients is increased to a smaller degree than in non-melanoma skin cancer, its potential morbidity and mortality has to be ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12276
更新日期:2016-01-01 00:00:00
abstract::Several treatment modalities are used for the treatment of acne scars with variable results. Recent studies showed that fractional radiofrequency may be an effective treatment modality for acne scars. The objective of this study was to assess the efficacy, safety, tolerability and patient satisfaction of fractional bi...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/dth.12275
更新日期:2016-01-01 00:00:00
abstract::Psoriasis is a chronic skin inflammatory disorder with frequent relapse. Ceramides and their key enzymes are deficient in the lesions, resulting in impaired epidermal permeability barrier, which correlates with disease severity. We evaluated the efficacy of linoleic acid-ceramide moisturizer (LA-Cer) as an adjunctive ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,随机对照试验
doi:10.1111/dth.12259
更新日期:2015-11-01 00:00:00
abstract::Switching psoriasis treatment is a common, accepted practice that is used to improve disease management and improve patient outcomes (e.g., when patients are experiencing suboptimal efficacy and/or tolerability with a given therapy). Historically, switching treatment was often performed to limit patients' cumulative e...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12267
更新日期:2015-11-01 00:00:00
abstract::The development of effective and well-tolerated biologic therapies has advanced the management of psoriasis by enabling clinicians to treat underlying disease mechanisms. Biologics approved for the treatment of moderate-to-severe psoriasis include three tumor necrosis factor alpha inhibitors and an interleukin-12/inte...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12251
更新日期:2015-07-01 00:00:00
abstract::Spontaneous remission occurs in less than 10% of patients suffering from alopecia areata (AA) totalis for more than 2 years. The efficacy of PUVA therapy is controversial due to recurrence of hair loss after cessation. We report two cases presenting with AA totalis and AA universalis. After hair regrowth, relapse of h...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12215
更新日期:2015-07-01 00:00:00
abstract::Tumor necrosis factor-alpha (TNF)-alpha inhibitors are licensed for patients with severe refractory psoriasis and psoriatic arthritis. However, TNF-alpha inhibitors have also been used off-label for various recalcitrant mucocutaneous diseases. This study aimed to evaluate the efficacy and safety of TNF-alpha inhibitor...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12222
更新日期:2015-05-01 00:00:00
abstract::Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic follicu...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12191
更新日期:2015-03-01 00:00:00
abstract::Vitiligo progression is attributed to immune system malfunctioning, thus immunomodulating compounds might be beneficial in stopping vitiligo progression which is a prerequisite for successful repigmentation. The goal of this study was to assess efficacy of acridone acetic acid, sodium salt (Na-AAA), an immunomodulatin...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/dth.12121
更新日期:2014-07-01 00:00:00
abstract::We report a case of Alternaria alternata cutaneous and pulmonary infection in a 62-year-old man after heart transplantation treated by azole antifungals. Alternaria spp. belong to a group of opportunistic dematiaceous fungi with worldwide distribution. The cutaneous form of the infection in human is very rare and occu...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12096
更新日期:2014-05-01 00:00:00
abstract::Leishmaniasis is an infectious disease caused by parasitic flagellates of the genus Leishmania. The authors present a case of 44-year-old man with Crohn's disease treated successfully with infliximab. This case report shows rare visceral leishmaniasis with cutaneous symptoms in an immunocompromised patient. Skin manif...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12083
更新日期:2014-05-01 00:00:00
abstract::Pruritus is a symptom that significantly affects the patient's quality of life in cutaneous T cell lymphoma (CTCL). The most effective treatments are those that address the condition itself; however, it is often not possible to control this symptom. Lymphoma-related pruritus normally becomes more severe as CTCL progre...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12113
更新日期:2014-05-01 00:00:00
abstract::Plantar warts are a common reason for dermatological consultations and their treatment can occasionally be a challenge. Plantar warts are benign lesions produced by the human papillomavirus (HPV) that often fail to respond to habitual treatment. Cidofovir is a potent antiviral drug that acts competitively, inhibiting ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12061
更新日期:2014-03-01 00:00:00
abstract::Adult colloid milium is a rare cutaneous deposition disorder that frequently involves areas of chronic sun exposure. The most common clinical presentation exhibits multiple, firm, and amber-colored papules that cluster to form large plaques. Histologically, there are masses of amorphous, eosinophilic material expandin...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12056
更新日期:2014-03-01 00:00:00
abstract::Epidermolytic acanthoma is an uncommon benign tumor with a predilection for the anogenital region, that is characterized histologically by epidermolytic hyperkeratosis. Most reported cases are asymptomatic while some are pruritic. Treatment of this condition is challenging and not well studied. We report a 55-year-old...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12068
更新日期:2014-03-01 00:00:00